a sudden, dramatic, and important discovery or development.
a major breakthrough in DNA research
同义词：
advancedevelopmentstep forwardleap forwardquantum leapstep in the right directionsuccessdiscoveryfindimprovementinnovationrevolutionprogressheadwayadvancement
2
denoting a symptomatic case of a disease occurring despite preventative medication, vaccination, or prior infection.
we're seeing more and more of these breakthrough infections
